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A Boston Biotech's Big Changes: Jobs Cut, Future Unclear

Seaport, USAThursday, November 20, 2025
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Company Background

  • Founded: 1999 (Originally as Panacea Pharmaceuticals in Maryland)
  • Relocated: 2017 to Delaware, renamed to Sensei Biotherapeutics
  • Current Location: Seaport area of Boston
  • Lease: Until September 2026

Recent Developments

  • Workforce Reduction: Let go of most employees (similar to last year)
  • Potential Sale: Considering selling the company
  • Financial Status:
  • Revenue: No revenue generated yet
  • Expenses: High research and operational costs
  • Cash Reserve: $25 million at the end of last year
  • Future Uncertainty: Unclear if they can continue without additional funding

Main Product

  • Name: Solnerstotug
  • Type: Monoclonal antibody
  • Purpose: Targeted treatment for cancer patients with limited options

CEO Statement

  • John Celebi: Noted positive results with solnerstotug but decided not to start a new study.
  • Focus: Winding down current work and optimizing outcomes for investors.

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