A Closer Look at Pemafibrate and Lifestyle Changes for Liver Health

People with type 2 diabetes and Metabolic dysfunction-Associated Steatotic Liver Disease (MASLD) often struggle with liver health. A recent study explored two different approaches to tackle this issue: a medication called pemafibrate and a serious lifestyle overhaul.

Pemafibrate: A Medication Approach

• Pemafibrate is a drug that targets specific receptors in the body.
• It is thought to improve liver function by:
• Reducing fat buildup
• Decreasing fibrosis (scarring of the liver)
• The study used FibroScan, a non-invasive tool, to measure these changes.

Lifestyle Changes: A Holistic Approach

• Diet and exercise can also make a big difference.
• The study examined how intense lifestyle modifications could impact liver health.
• Both approaches aimed to lower levels of a protein called soluble Dipeptidyl Peptidase-4 (sDDP-4)/CD26, which is linked to liver function.

Study Findings

• Both pemafibrate and lifestyle changes had positive effects on liver health.
• However, the exact benefits and mechanisms still need more research.
• Lifestyle changes often come with fewer side effects compared to medication.

Conclusion

For those dealing with type 2 diabetes and MASLD, this study offers hope. It shows that there are multiple paths to improving liver health. However, it's crucial to consult with healthcare providers to determine the best approach for each individual.