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Brain Changes in New Moms: A Closer Look

Spain, MadridThursday, March 5, 2026
Scientists in Spain studied how pregnancy hormones can change the brain’s gray matter. They used MRI scans and urine tests on 179 women, tracking changes before, during, and after pregnancy. The research showed that gray matter – the part of the brain involved in thinking and feeling – can shrink by about 5 % while a woman is pregnant. This loss isn’t harmful; instead, it seems to help the brain adapt for motherhood. After birth, gray matter grows back, but not all of it returns to its original size. The rebound is linked with better bonding and less negative feelings toward the baby at six months.
The study focused on two estrogen types that rise during pregnancy and fall sharply after delivery. The scientists say these hormonal shifts remodel the brain’s structure, making it more efficient for caring behaviors. To prove that the changes are due to pregnancy itself and not just becoming a parent, researchers also studied queer couples where only one partner was pregnant. The results were the same for the pregnant partner, showing that biology drives the brain changes. The researchers want future work to measure how much time parents spend with their babies and how that affects brain recovery. They hope this knowledge will help design better support for mothers during pregnancy and after birth, especially in times when mental health is at risk.

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