Imagine being able to give your furry friend a few extra years of life, free from age-related health issues. This is exactly what a team of scientists at Loyal, an animal pharmaceutical company, are working towards. Their research focuses on developing drugs that can extend the lifespan of dogs, big and small.

The team's efforts are centered around a hormone called insulin-like growth factor 1 (IGF-1), which plays a crucial role in dog size. In larger breeds, IGF-1 levels are higher, making them more prone to age-related health issues. The scientists have created a drug called LOY-001, which reduces IGF-1 levels, potentially prolonging a large dog's lifespan.

But that's not all. The company is also working on a daily pill version of the drug, called LOY-003, specifically designed for large dogs. Another drug, LOY-002, targets a different approach to improve a dog's metabolic health, which could extend the lives of senior dogs of all sizes.

The team at Loyal is well aware of the importance of ensuring that their drugs do not compromise a dog's quality of life. As Dr. Brennen McKenzie, the company's director of veterinary medicine, emphasizes, "We want to keep dogs healthy and happy."

The potential benefits of this research go beyond just improving the lives of dogs. It could also lead to breakthroughs in human medicine. "Deciphering the secrets to better longevity in dogs could someday lead to drugs that can do the same for humans," Dr. McKenzie notes.

Can Dogs Live Longer? Scientists Make Breakthrough

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