Atomic Force Microscopy, or AFM, is like a tiny detective in the world of biology. It works by gently prodding surfaces with a super-sharp tip, giving scientists an incredibly close look at things too small to see with regular microscopes. Over time, scientists have gotten better at understanding how this tip interacts with surfaces, making AFM images even clearer.
But AFM isn't just for looking; it can also poke and prod biological systems, helping us understand how physical forces affect living things. This process, called mechanotransduction, is like a secret language where physical signals are translated into biological responses. By applying controlled forces, AFM helps decipher this language.
From studying single molecules to entire tissues, AFM plays a dual role: a sensor that captures detailed images and a tool that tests biological systems. However, it's not all smooth sailing. Scientists face challenges in refining AFM's techniques and interpreting the data it provides. Yet, the future looks promising with potential advancements on the horizon.
