Exploring MIBiG 4. 0: A Community Effort in Biosynthetic Gene Cluster Curation

Biosynthetic gene clusters (BGCs) are like tiny factories in cells that produce special molecules with big impacts. These molecules, known as secondary metabolites, can be used in medicine, agriculture, and engineering. To share information about these BGCs in a standardized way, the MIBiG data standard and repository was launched in 2015. MIBiG has been updated regularly to keep up with new findings in natural product research. Let's dive into MIBiG version 4. 0, a significant update that involved a massive community effort. In this version, 267 people from around the world came together to make 8, 304 edits. They added 557 new entries and updated 590 existing ones, bringing the total to 3, 059 curated entries. Quality was a top priority, with automated data validation and a new peer-review model ensuring accuracy. MIBiG 4. 0 also aims to involve more scientists and switch to a rolling release model for continuous updates. This update is a testament to the power of global collaboration in scientific research. It shows how many minds working together can advance our understanding of these tiny cellular factories and their products.

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