Get ready to set your fantasy football lineups for Week 6! Let's take a look at the players you should start, sit, and keep an eye on.

Quarterbacks are a hot topic this week. Dak Prescott is a top pick against the Lions, who let Geno Smith throw for a career-high 395 yards in Week 4. Daniel Jones is also looking good after a rough start, with six touchdowns and only one interception over the past four weeks. But hold off on Josh Allen this week—he's struggled on the road, and the Jets' defense has been tough.

Running backs are another key position. D’Andre Swift has been on fire, finishing as the RB2 and RB3 over the past two weeks. He's facing the Jaguars, who are one of the friendliest defenses to running backs this season. Tyrone Tracy Jr. could be a sleeper pick if Devin Singletary is still injured. But be cautious with Rico Dowdle—the Lions have been tough on running backs, and Dowdle hasn't shown much rushing ability.

Wide receivers are always important in fantasy football. Jalen Tolbert had a great game in Week 5 with 87 receiving yards and a touchdown. He's facing the Lions' defense, which has allowed the most receiving yards per game to wide receivers this season. Tank Dell could be a sleeper pick with Nico Collins on injured reserve. But Christian Kirk might struggle this week with Evan Engram expected to return and the Jaguars facing a tough Bears defense.

Tight ends are a bit of a gamble this week. Sam LaPorta could be a good pick, as the Lions need to get their tight end more involved in the offense. Theo Johnson is a rookie to watch, with career highs in receptions and yards in Week 5. But Dallas Goedert might not be the best pick this week, with both A.J. Brown and DeVonta Smith expected to return.

Fantasy Football Week 6: Top Picks, Busts, and Sleepers

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