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Finding Key Cancer Genes: A New Approach

Sunday, January 12, 2025
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Cancer, we know, is caused by tweaks in our genes. Scientists are hot on the trail of these mutated drivers, hoping to shed light on how cancer starts. But figuring out which genes are common or unique to different cancers is no walk in the park. This study aims to change that. Scientists have whipped up two clever models to find common cancer genes across many cancer types (let's call this ComMDP), and genes that are specific to a cancer type (let's call this SpeMDP). They tested these models on pretend data first, just to make sure they work. Then, they tried them out on real cancer data from 12 different cancers. Ta-da! They found some cool pathways that could help explain how cancer gets started. For example, they found some common paths between breast and ovarian cancer, and even some special paths for a blood cancer called LAML. Plus, they found new suspect genes that could be playing a part in cancer. All this could help tailor treatments just for you, making cancer care even more personal.

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