How Amazonian Brew May Help Fight Cocaine's Brain Damage

Ayahuasca, a plant-based drink used in spiritual ceremonies, contains two main active ingredients: DMT and harmine.

• DMT: A psychedelic compound.
• Harmine: Enhances the body's absorption of DMT.

Recent Scientific Findings

Scientists investigated whether these compounds could protect brain cells from the harmful effects of cocaine.

Lab Testing on Human Brain Cells

• Exposure to Compounds: Cells were exposed to varying amounts of DMT, harmine, and cocaine.
• Results: When combined with cocaine, DMT and harmine reduced cell death, suggesting potential protective effects.

Impact on Cell Death Proteins

• Caspase-8: A protein involved in cell death.
• Finding: DMT and harmine reduced caspase-8 activity, further supporting their protective potential.

Important Considerations

• Lab Study Limitations: The research was conducted in a lab, not on humans.
• Further Research Needed: More studies are required to confirm real-world applications.
• Ayahuasca Risks: A powerful substance with potential risks; should only be used under proper guidance.