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How Gut Bacteria Can Help a Sick Heart

Saturday, July 19, 2025
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The Global Impact of Heart Problems

Heart problems are a significant global concern, with damage to the heart muscle being a major issue. Scientists have been exploring the potential of probiotics—good bacteria—to protect the heart.

A Special Yogurt Bacteria

One type of bacteria, Lacticaseibacillus paracasei, was found in a special kind of yogurt made from yak milk. Researchers tested this bacteria on mice with heart damage caused by a strong medicine.

Remarkable Results

The mice that received the bacteria showed:

  • A 14% increase in body weight
  • A 19% increase in heart size
  • Significant improvements in blood tests, with levels of harmful substances dropping by more than half in some cases.
  • Improved heart function, including:
  • Shortened time for the heart to recharge
  • Reduced abnormal signals

Microscopic Improvements

Under a microscope, scientists observed:

  • Less scarring in heart tissue
  • Fewer dying cells
  • Better energy management in heart cells
  • Improved cleanup of damaged parts

Gut Bacteria Balance

The bacteria also helped balance the gut microbiome by:

  • Increasing good bacteria
  • Decreasing bad bacteria

The Science Behind the Benefits

Researchers discovered that the bacteria produce certain chemicals that may be responsible for these protective effects. One such chemical, 5-hydroxymethylfurfural, showed protective properties when tested on heart cells in a lab.

Future Implications

This study provides valuable insights into how probiotics might help maintain heart health. It suggests that Lacticaseibacillus paracasei could be a promising candidate for new treatments. However, since the research was conducted on mice, further studies on humans are necessary.

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