Red Light Shines Hope on Psoriasis Treatment

Understanding Psoriasis

Psoriasis is a chronic skin condition characterized by:

• Red, itchy, and scaly patches
• Overactive immune system

Exploring New Treatments

Scientists are investigating innovative approaches to manage psoriasis. One such method involves using red light from LEDs with a wavelength of 660 nm. This light may help:

• Reduce inflammation
• Promote skin healing

Study Overview

Methodology

• Subjects: Mice induced with psoriasis using imiquimod cream (mimics psoriasis symptoms)
• Duration: 12-day treatment period
• LED Exposure: Starting from day 4, mice were exposed to red LED light every other day for a total of five sessions

Results

• Symptom Reduction:
• Less severe symptoms
• Reduced skin thickness and redness
• Microscopic Improvements:
• Fewer mast cells (involved in allergic reactions and inflammation)
• More evenly distributed collagen fibers (improves skin strength and elasticity)
• Limitations:
• Did not reduce the overall thickness of the skin's deeper layers
• Did not prevent changes in the spleen (immune system organ)

Protein Analysis

• Inflammatory Proteins:
• IL-1β and TNF-α levels were reduced in the skin
• IL-22 levels were reduced in the blood
• Other proteins did not show significant changes

Conclusion

• Red LED light shows promise in easing psoriasis symptoms by reducing inflammation
• Not a cure-all: Does not address all aspects of psoriasis
• Potential Addition: Could be a helpful complement to current treatments