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San Diego Lab Space: Empty Buildings, New Moves

San Diego, CA, USA,Saturday, April 18, 2026

San Diego’s research labs are largely empty—about one‑third of the space remains unused, a figure that rivals its highest levels in recent history.
City rental rates are falling and landlords are offering deeper discounts, prompting a handful of companies to step in.

A Mixed Market Landscape

  • Venture capital is returning and investors are feeling more optimistic.
  • Yet, the total leased space this quarter is only half of what it was a year ago.
  • Analysts note that the commercial real‑estate market is still in recovery mode.

Biotech’s Shift Toward Premium Facilities

  • Major biotech firms are relocating to new, high‑quality buildings in Torrey Pines and Del Mar Heights.
  • These moves signal a shift from cost‑cutting to investing in better facilities and growth.

International Presence Expands

  • A Beijing company will open a new office near Qualcomm.
  • A Taiwanese firm has built a $30 million factory in Sorrento Valley.
  • These arrivals underscore San Diego’s appeal to global talent and its affordable premium space.

The Bottom Line

  • Leasing activity fell sharply in Q1: only 223,000 sq ft signed versus historical averages of 450,000–580,000 sq ft.
  • Downtown labs are most affected, with only 10% occupancy.
  • Many new buildings from the 2021‑22 boom remain vacant, highlighting a supply‑demand mismatch.

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