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Thanksgiving Feast: Food and Medication Mix-Ups to Avoid

USAFriday, November 21, 2025
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Thanksgiving is a time for big meals and family, but it's also a time to be careful with food and medicine. Some foods can mess with common medicines, causing problems.

Food and Medicine Interactions

  • Leafy Greens like spinach and kale have vitamin K, which helps blood clot.
  • If someone is on blood thinners, eating too much or too little of these greens can be risky.

  • Dairy products, like milk and cheese, are good for bones but can interfere with certain antibiotics.
  • To avoid this, it's best to take antibiotics a few hours before or after eating dairy.

  • Grapefruit juice can also cause issues.
  • It blocks enzymes in the liver that break down some medicines, making side effects worse.
  • This is especially important for people taking statins, blood pressure meds, or antidepressants.

  • Alcohol is another thing to watch out for.
  • It can make some medicines, like antidepressants and sedatives, more potent, leading to drowsiness or unsteadiness.
  • It can also strain the liver and mess with diabetes medications, making blood sugar harder to control.

Food Safety During Thanksgiving

  • Raw turkey, undercooked stuffing, and food left out too long can cause food poisoning.
  • The CDC advises keeping frozen turkey at 0°F or below until ready to thaw.
  • Thawing should be done in the fridge, in cold water, or in the microwave, never on the counter.
  • Cooking the turkey to an internal temperature of 165°F is crucial, and using a food thermometer helps ensure safety.
  • Stuffing the turkey is not recommended for food safety reasons.
  • Leftovers should be stored properly and eaten within four days or frozen for longer storage.

Avoiding Overeating and Other Risks

  • Eating too much or too fast can lead to indigestion, heartburn, and bloating.
  • It's also easy to choke if you're not careful.
  • Drinking too much alcohol can increase the risk of accidents.
  • To enjoy the feast without issues, it's best to:
  • Eat regular meals before the big meal and avoid arriving too hungry.
  • Eat slowly and mindfully to help you feel full and enjoy the food more.
  • Resist second helpings and save leftovers for later.

Long-Term Health Considerations

Thanksgiving is a time to enjoy, but it's important to think about long-term health.

  • One big meal won't ruin your health, but consistent healthy eating habits will support your well-being in the long run.

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