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Weight Loss Drugs Get a Mental Health Clearance

USAThursday, January 15, 2026
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The FDA has made a significant change. They want to remove the suicide warning from popular weight loss drugs like Wegovy and Zepbound. This decision comes after a thorough review of extensive data, which found no link between these drugs and suicidal thoughts.

Background on GLP-1 Drugs

These drugs, known as GLP-1, were initially developed to help people with type 2 diabetes. They work by making individuals feel full, leading to reduced food intake and weight loss.

Study Findings

The FDA analyzed data from nearly 108,000 patients. Over 60,000 took GLP-1 drugs, while the rest received a placebo. The results showed no increased risk of suicidal thoughts or other mental health issues like anxiety or depression.

Previous Concerns

This is not the first time the FDA has investigated this matter. In 2024, they stated that the data was insufficient to rule out a small risk. However, with more information now available, they are confident there is no connection between these drugs and suicidal thoughts.

Implications for Users

This is good news for individuals using these medications, as it reinforces their safety. However, it remains crucial to consult a doctor about any concerns.

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