Bioinformatics is a field that combines biology and computer science to solve complex problems. It's like giving computers the ability to understand and analyze biological data. This field has revolutionized how we study life and health. One of the key figures in this revolution is a pioneer who has
In the world of medicine, a huge milestone was reached in 2024. It was the 15th birthday of ChEMBL. It is a big deal because ChEMBL is a massive, free-to-use database. It is like a giant library filled with information about drugs and how they work. This library is hosted by the European Bioinfor
Scientists have found some interesting things about DNA damage repair genes in people with oral cancer in Pakistan. They looked at five specific genes: TP53, ATR, ATM, CHEK1, and CHEK2. Using advanced tools, they found 42 mutations, with some being completely new. Out of these, 28 were nonsynonymous
Osteoarthritis (OA) and metabolic syndrome (MetS) are both big problems that get worse as we age. But what's really going on inside our bodies that makes this happen? Scientists dug into public databases to find genes that change with age and might be linked to these conditions. They found 20 genes
Preeclampsia (PE) is a serious issue during pregnancy. It's tough to spot early and even tougher to treat. Recently, scientists have been looking into something called ferroptosis. This is a type of cell death that needs iron to happen. Researchers think it might play a big role in what causes PE. S
Let's dive into the world of traditional Chinese medicine and explore the surprising benefits of a classic remedy called Shaoyao Gancao Decoction, or SGD for short. This isn't your average herbal tea; it's a powerful blend of two specific herbs: Paeoniae Radix Alba and Glycyrrhizae Radix et Rhizoma.
Copper, a metal we often think of as a material for coins or wires, is now being studied for its role in cancer. Researchers have found that copper can help control how cells die in breast cancer. This process is called cuproptosis. Scientists have been looking into how copper-related genes (CRGs) w
Lung cancer is a big problem around the world. The gene PHKA1 has been found to play a significant role in this disease. Scientists used computer tools to study PHKA1 in lung cancer. These tools showed that PHKA1 levels are high in lung adenocarcinoma across different stages of the cancer. This fin
First, let's imagine a tiny powerhouse inside our cells. These are called mitochondria, and they keep our cells running smoothly. Now, when these powerhouses get damaged, our bodies have a way to clean house, and that's where something called mitophagy comes in. It's a process where cells get rid of
The world is getting a lot more complex, with issues like bioterrorism, climate change, and urbanization on the rise. All of these factors have led to the emergence of new diseases, especially in pets and farm animals. Pathogens are sneaking into new populations, causing issues with reproduction, pr
