How EGFR Gets Wrapped Up: Different Paths for Different Ligands
The epidermal growth factor receptor, or EGFR, helps cells grow and become specialized. But when things go wrong, EGFR can cause cancer. There are eight molecules, called ligands, that activate EGFR, with two main ones being epidermal growth factor (EGF) and transforming growth factor-α (TGF-α). Sci