LND
kcnq1 variant
science

Heart Rhythm Disrupted by a Tiny Gene Change

July 19, 2026

A single alteration in the KCNQ1 gene, swapping a D for an N at position 673, stops the heart from speeding up its electrical pulse when adrenaline is present. The change weakens a potassium channel that normally helps reset the heart’s rhythm after each beat. In people carrying this mutation, the e

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