LND topic: tme page 278

tme

Boosting Dasatinib's Power: How Febuxostat Fights Leukemia

November 27, 2024

Dasatinib is a key medicine for treating chronic myeloid leukemia (CML), but some patients' cells become resistant to it. This resistance is partly due to a protein called ABCG2 that kicks dasatinib out of the cells. Febuxostat, normally used to treat gout, can block ABCG2. A recent study looked int

health

Unraveling the Potential of Spirooxindole Drugs in Cancer

November 27, 2024

Cancer remains a major health threat globally, making the search for new treatments crucial. Scientists are now exploring spirooxindole drugs as a promising avenue. These drugs have a distinctive structure that allows them to target various factors involved in cancer growth, such as kinases and rece

health

Biden's Plan: Making Weight Loss Drugs Affordable for Seniors and the Needy

November 26, 2024

The Biden administration has come up with a new idea to help people who are overweight. They want Medicare and Medicaid to cover the cost of weight loss drugs for people who need them. This would make it much cheaper for people to get these drugs, which can be really expensive right now. Medicare u

health

How Cancer Treatment Affects Daily Life for Esophageal Cancer Patients

November 26, 2024

Esophageal cancer (EC) patients undergo significant changes during and after their treatment with chemoradiotherapy. These changes include shifts in body mass index (BMI), performance status, nutrition status, symptom distress, and physical fitness. A recent study explored how these factors evolve o

business

Meet Kohl's New CEO: Ashley Buchanan from Michaels

November 26, 2024

Kohl’s has a new leader on the way! The company recently announced that Ashley Buchanan, currently the CEO of Michaels Companies, will take over as their CEO in January. Tom Kingsbury, the current CEO, will step down on January 15 but will stay on as an advisor until May. Buchanan has been leading M

health

Hot Flashes and Menopause: Who's Getting Help and Who's Not?

November 26, 2024

Let's talk about hot flashes and menopause. You might be surprised to know that not everyone gets help with these symptoms. A recent study looked into how common it is for women in the US, aged 40-64, to be diagnosed with hot flashes related to menopause. They found that around 79 out of every 1, 00

health

Head-to-Head: How Lercanidipine and Amlodipine Stack Up for Hypertension

November 26, 2024

Hypertension, often called high blood pressure, is a common health issue. Two medicines, lercanidipine and amlodipine, are used to treat it. Both are calcium channel blockers, but lercanidipine is newer. This study wants to see which one is better at preventing serious heart problems in people with

health

HIV: Big Progress, But Not Time to Celebrate Yet

November 26, 2024

Great news! The world is seeing fewer new HIV infections and deaths. This is a big win, especially in sub-Saharan Africa, where numbers have dropped the most. But, there's still work to do. Some places, like Eastern Europe and the Middle East, are seeing more new cases. We're far from the 2030 targe

politics

Trump's Plan to Ax Education Department: Easier Said Than Done?

November 26, 2024

President-elect Donald Trump's promise to do away with the U. S. Department of Education sounds simple, but experts say it's anything but. The plan involves complex logistics, congressional approval, and redirecting federal programs. It's doubtful that Congress will go along with it, and if it happe

science

Fixing MoS 2 Device Flaws: A Liquid Solution

November 26, 2024

Making semiconductors often leaves tiny issues, like dangling bonds and charge traps, on channels and interfaces. Fixing these can be tough, especially with small structures and thin materials like MoS 2 . High-energy treatments might cause more harm than good. So, scientists turned to hydrogen io