Galantamine, known for its role in managing brain disorders, has been modified to create potential drugs for Alzheimer's disease. Scientists designed and synthesized a variety of galantamine analogues, one of which, named C2, showed great promise. By adding a benzylpyridine ring to galantamine's hyd
Ever wondered how our brain remembered things or paid attention? Laszlo Zaborszky, a distinguished professor, has spent his career figuring that out. At 80, he's still inspiring young scientists. His big discovery? The basal forebrain, a tiny part of our brain, is crucial for learning and memory. It
Did you know that tiny worms like C. elegans can teach us a lot about human diseases? Scientists have been studying a protein called sigma-1 receptor (σ1R) to understand how it interacts with different drugs, or ligands, and affects lifespans. They found that some drugs stick better to the σ1R prote
Alzheimer's disease is a tough condition that affects many older adults. Scientists often use a test called APOE genetic testing to see who might get it. Latinos are a group that hasn’t been studied much for this disease, but they will be hit hard by it in the future. To help educate and advise Lati
Caring for someone with Alzheimer's disease or other dementias can be tough. As the condition worsens, more help is needed from family and friends. This takes a toll—financially, mentally, and physically. Enter CareVirtue, an online tool designed to bring everyone in the care network together. It he
Alzheimer's disease is a major challenge for modern medicine, as we still lack drugs that can truly stop or slow its progression. The number of people affected by Alzheimer's is expected to rise dramatically in the coming years. One big reason why finding new treatments is so hard is that many diffe
You know how some people worry about inheriting Alzheimer's disease? Well, it turns out that your lifestyle can make a big difference, even if you have a genetic predisposition. A better lifestyle means you're less likely to develop dementia and your brain stays sharper longer. But what does a "bet
Could flashing lights while you sleep help fight dementia like Alzheimer's? Scientists are exploring this idea with a 40 Hz visual stimulation technique. This non-invasive method is being tested during different sleep stages. The goal? To see if it can boost brain activity and potentially slow down
A study recently explored whether resistance exercises could help lower the risk of falls among individuals with Alzheimer's disease. The focus was on how such workouts might improve muscle strength, reduce the fear of falling, and enhance the ability to perform daily tasks. Additionally, the study
Did you know that Alzheimer's disease can mess with a person's mood and voice? A recent study dug into this, asking folks with early-stage Alzheimer's and others without it to fill out questionnaires. These forms helped measure depression and how people felt about their voice. The results? People wi
