Osteogenesis imperfecta (OI) is a rare genetic condition that affects the body's connective tissues, making bones unusually fragile. This condition is usually identified through clinical observations, but genetic testing can provide additional insights. In Romania, a group of nine patients with typ
The human body is a marvel of teamwork. One amazing example is how kidneys, blood vessels, and nerves all develop together. This isn't just about one thing happening after another. It's a complex dance where each part influences the others. Let's dive into this fascinating process. First off, consi
Pathological angiogenesis is a major player in ischemic retinal diseases. These diseases are a leading cause of blindness globally. The process involves the growth of new, abnormal blood vessels. This happens due to changes in how genes are expressed in response to shifts in metabolism within endoth
The bone is a lot more than just a support structure. It's also a player in the body's energy game. It can influence how fat is made and how energy is managed throughout the body. This is all thanks to certain factors that the bone releases. One of these factors is KIAA1199. It's a substance made by
The world of biology is full of surprises. Researchers have uncovered an unexpected link between two proteins, CDK8 and CDK19, and male fertility in mice. These proteins are part of a larger group that helps control how genes are turned on and off. To understand their role, scientists created mic
The number of segments in the trunk of vertebrates varies greatly. This diversity is fascinating, but the process behind it is not well understood. Scientists believe that the number of segments is set during early development. This happens when cells in a specific area, called the pre-somitic mesod
Scientists have found that certain mutations often go hand in hand in blood cancers. These mutations can make the disease worse and harder to treat. One such pair is mutations in the genes TET2 and TP53. These mutations can work together to make blood cancers more aggressive. They can also creat
PNH, or Paroxysmal Nocturnal Hemoglobinuria, is a unique condition. It's not cancerous, but it's a problem with your blood cells. It all starts with a genetic glitch. There's a specific gene, PIGA, that can have a mutation. This mutation creates a mutant stem cell, which is the first step in the pro
Skin is the body's biggest shield, constantly fending off environmental dangers and harmful substances. These threats can sometimes lead to skin cancer. Traditional chemotherapy has been a go-to treatment, but its high cost and nasty side effects have left many searching for better options. This
Imagine tiny bubbles, so small you can't see them with the naked eye, floating around in our bodies. These are called exosomes, and they're like little messengers that help cells talk to each other. When it comes to cancer, these bubbles can be a big problem. Cancer cells use these exosomes
